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DSS Crosslinker
CAS No. 68528-80-3
DSS Crosslinker ( —— )
产品货号. M22922 CAS No. 68528-80-3
DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm that are used to conjugate proteins.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | ￥332 | 有现货 |
|
| 500MG | ￥462 | 有现货 |
|
| 1G | ￥599 | 有现货 |
|
生物学信息
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产品名称DSS Crosslinker
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm that are used to conjugate proteins.
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产品描述DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm that are used to conjugate proteins. DSS crosslinker can be used to conjugate or crosslink intracellular proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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同义词——
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通路Antibody Drug Conjugates (ADC)
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靶点ADCs Linker/Click Chemistry
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受体Non-cleavable
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研究领域——
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适应症——
化学信息
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CAS Number68528-80-3
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分子量368.34
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分子式C16H20N2O8
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(ON1C(CCC1=O)=O)CCCCCCC(ON2C(CCC2=O)=O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
产品手册
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