DSS Crosslinker

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

DSS Crosslinker 是一种不可裂解的 ADC 连接剂，用于合成抗体药物偶联物 (ADC)。它是一种可渗透细胞膜的同双功能交联剂。 DSS 交联剂在 8 个原子（11.4 埃）间隔臂的两端具有胺反应性 NHS 酯，用于缀合蛋白质。

DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm that are used to conjugate proteins. DSS crosslinker can be used to conjugate or crosslink intracellular proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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Antibody Drug Conjugates (ADC)

ADCs Linker/Click Chemistry

Non-cleavable

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68528-80-3

368.34

C16H20N2O8

>98% (HPLC)

In Vitro:?DMSO : 250 mg/mL (678.72 mM)

O=C(ON1C(CCC1=O)=O)CCCCCCC(ON2C(CCC2=O)=O)=O

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(-20℃)

With Ice Pack

≥ 2 years